U.S. to purchase a whole bunch of tens of millions extra doses of Pfizer vaccine to donate to the world

“This assembly is about increasing and enhancing our shared efforts to defeat COVID-19, constructing out from earlier gatherings of world leaders and ministers in fora just like the G7, G20, and Act Accelerator to rally civil society, NGOs, philanthropists, and business together with world leaders and align on a typical imaginative and prescient for defeating COVID-19 collectively,” White Home press secretary Jen Psaki mentioned in a press release.

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When You Ought to Get Your COVID Booster Shot

After a protracted and tense assembly as we speak, an FDA committee unanimously really helpful that the company authorize third pictures of the Pfizer COVID-19 vaccine for People who’re over 65 or at excessive danger of extreme COVID. The vote got here after the panel voted overwhelmingly in opposition to the unique query up for its consideration: authorizing boosters for everybody over 16. If the FDA follows the committee’s advice (as is predicted), a CDC committee will assist refine these tips subsequent week, clarifying which teams qualify as “excessive danger.”

Whilst we await these last selections, the nation’s summer season wave of COVID infections looks as if it’s starting to cross. Instances and hospitalizations are trending barely downward. Now that we now have extra readability about whether or not (and which) People want booster pictures—and provided that so many individuals are already getting boosters, eligibility be damned—extra questions loom:

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FDA assessment stays impartial on boosters forward of vital Friday vote at the same time as Pfizer pushes extra photographs

“There are already docs recommending booster doses, and there are sufferers who’ve gone on the market, by hook or criminal, and have obtained boosters already,” mentioned William Schaffner, an infectious illnesses professor at Vanderbilt College Faculty of Medication. “The typical affected person and the common physician assume a advice with a capital R has already been made. Washington received out forward of its skis somewhat bit.”

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Theranos and COVID-19 Are Related

If you’re regulating new expertise for diagnostics, it’s laborious to stability velocity and security.

Nic Coury / AP

Final week, prosecutors and protection attorneys made opening statements within the felony trial of Elizabeth Holmes, the previous CEO of Theranos, who’s accused of defrauding buyers and sufferers with false guarantees of low cost, speedy blood exams. The following day, the Biden administration introduced a plan to buy 280 million low cost, speedy COVID-19 exams—an motion for which some lawmakers have been advocating for greater than a yr. The serendipity of those two occasions exposes an unresolved rigidity in well being care: How will we stability the dangers of disruptive innovation with the mortal prices of administrative inertia?

Theranos and COVID-19 testing are each cautionary tales of failed medical oversight, however the morals flip from one case to the opposite. Every addresses, in its method, how a lot management the FDA ought

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Biden to ask world leaders to make new commitments to struggle coronavirus

“Through the Summit, President Biden will name on chiefs of state, heads of presidency and worldwide organizations, enterprise, philanthropic, and non-governmental leaders to come back collectively to decide to ending the COVID-19 pandemic,” in accordance with a replica of 1 invitation reviewed by The Put up. “Individuals will establish concrete actions and set the bold targets wanted to attain that aim and put together the world for future well being safety threats.”

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COVID Hospitalization Numbers Can Be Deceptive

No less than 12,000 Individuals have already died from COVID-19 this month, because the nation inches by its newest surge in instances. However one other worrying statistic is usually cited to depict the risks of this second: The variety of sufferers hospitalized with COVID-19 in the US proper now could be as excessive because it has been for the reason that starting of February. It’s even worse in sure locations: Some states, together with Arkansas and Oregon, not too long ago noticed their COVID hospitalizations rise to larger ranges than at any prior stage of the pandemic. However how a lot do these latter figures actually inform us?

From the beginning, COVID hospitalizations have served as an important metric for monitoring the dangers posed by the illness. Final winter, this journal described it as “probably the most dependable pandemic quantity,” whereas Vox quoted the heart specialist Eric Topol as saying

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Phrases describing psychological well being can stigmatize. That’s painful and dehumanizing.

And, in any case these years, I now perceive that I’m not “irregular.” To that time, years in the past, my mom, a social employee who suffered from continual despair, instructed me one afternoon on the seashore, “I’m so blissful that everybody within the household is in remedy,” an acknowledgment that all of us suffered from anxiousness or despair. My mother, who died 4 years in the past, absolutely would have agreed with the consultants in the present day who say that overtly speaking about psychological well being can break down the stigma related to totally different situations.

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The Sweetgreen CEO’s Merciless, Harmful Pandemic Plan

Jonathan Neman actually appeared to suppose he was onto one thing. Final week, in a prolonged, now-deleted publish on LinkedIn, the CEO and co-founder of the upscale salad chain Sweetgreen expounded on a subject which may appear just a little far afield for a restaurant govt: tips on how to finish the pandemic. “No vaccine nor masks will save us,” he wrote. (The vaccines, it must be famous, have up to now proved to be near-miraculously efficient at saving those that get them.) As an alternative, he lamented that Individuals are just too fats to outlive COVID-19, a actuality that he says could possibly be addressed with “well being mandates.”

Neman didn’t go into many specifics about how well being must be mandated, or what such mandates would imply for disabled folks, although efforts at nationwide enchancment that concentrate on these designated as physiologically undesirable have traditionally ended poorly for

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The ‘Sterilizing Immunity’ Delusion: No Vaccine Is Good

In 1846, the Danish doctor Peter Ludvig Panum traveled to the Faroe Islands in the hunt for measles. The rocky archipelago, which sits some 200 miles north of Scotland, had been slammed with an outbreak, and Panum was dispatched by his authorities to analyze. The journey predated the formal discovery of viruses and antibodies by a number of a long time, however Panum nonetheless stumbled upon a beguiling immunological pattern: Dozens of the islands’ eldest residents, who had survived one other measles epidemic in 1781—65 years earlier—weren’t getting sick this time round. “Not one, so far as I might discover out by cautious inquiry,” he wrote in a treatise, “was attacked the second time.”

Panum in all probability didn’t notice it then, however his observations helped spark the inklings of a notion that may survive his century, into the following, and the following: the promise of good immunity, a safety

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Telemedicine — a boon for a lot of within the pandemic — threatened with cutbacks

Different sufferers are dropping entry to telemedicine due to a technological gulf. For in-state sufferers, some suppliers proceed to reimburse video visits at comparable charges to in-person, however this has change into rare for phone visits. Medicare introduced it is going to now not provide cost parity for video and phone visits after the federal public well being emergency order expires (most lately prolonged till Oct. 18, 2021, by Xavier Becerra, secretary of Well being and Human Providers). As of March, solely 22 states required insurers to even cowl phone visits.

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Waning Immunity Is Not a Disaster, Proper Now

Vaccines don’t final without end. That is by design: Like most of the microbes they mimic, the contents of the pictures stick round solely so long as it takes the physique to eradicate them, a tenure on the order of days, maybe a number of weeks.

What does have endurance, although, is the immunological impression that vaccines depart behind. Defensive cells research decoy pathogens whilst they purge them; the recollections that they kind can final for years or a long time after an injection. The realized response turns into a reflex, ingrained and automated, a “sturdy immune reminiscence” that far outlives the shot itself, Ali Ellebedy, an immunologist at Washington College in St. Louis, advised me. That’s what occurs with the COVID-19 vaccines, and Ellebedy and others advised me they count on the reminiscence to stay with us for some time but, staving off extreme illness and demise from the

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